Repolarization abnormalities, arrhythmia and sudden death in canine tachycardia-induced cardiomyopathy.

@article{Pak1997RepolarizationAA,
  title={Repolarization abnormalities, arrhythmia and sudden death in canine tachycardia-induced cardiomyopathy.},
  author={Peter H. Pak and H. Bradley Nuss and Richard S. Tunin and Stefan K{\"a}{\"a}b and Gordon F. Tomaselli and Eduardo Marb{\'a}n and David A. Kass},
  journal={Journal of the American College of Cardiology},
  year={1997},
  volume={30 2},
  pages={576-84}
}
OBJECTIVES This study sought to determine whether the canine model of tachycardia-induced heart failure (HF) is an effective model for sudden cardiac death (SCD) in HF. BACKGROUND Such a well established HF model that also exhibits arrhythmias and SCD, along with repolarization abnormalities that could trigger them, may facilitate the study of SCD in HF, which still eludes effective treatment. METHODS Twenty-five dogs were VVI-paced at 250 beats/min for 3 to 5 weeks. Electrocardiograms were… CONTINUE READING
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