Reply to the Commentary “To Gorelenkova Miller and Mieyal (2015): Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases” by M. Kato

@article{Miller2016ReplyTT,
  title={Reply to the Commentary “To Gorelenkova Miller and Mieyal (2015): Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases” by M. Kato},
  author={Olga Gorelenkova Miller and J. Mieyal},
  journal={Archives of Toxicology},
  year={2016},
  volume={90},
  pages={1019-1020}
}
S-glutathionylation) that are particularly relevant to cell signaling. Since interand intramolecular disulfides and glutathionyl mixed disulfides are known to be reductively reversed by the thioredoxin and glutaredoxin enzyme systems, respectively (Gallogly et al. 2009), it is conceivable that these enzymes may regulate RET function. Thus, reversible cysteine adducts may have a role as precursors to RET dimerization, serving as a switch mechanism for RET tyrosine kinase signaling. In this… Expand

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Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases
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Parkinson Disease-associated DJ-1 Is Required for the Expression of the Glial Cell Line-derived Neurotrophic Factor Receptor RET in Human Neuroblastoma Cells*
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Absence of Ret Signaling in Mice Causes Progressive and Late Degeneration of the Nigrostriatal System
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