Reply: Where are the somatosensory evoked potentials recorded from DBS leads implanted in the human pedunculopontine tegmental nucleus generated?

  title={Reply: Where are the somatosensory evoked potentials recorded from DBS leads implanted in the human pedunculopontine tegmental nucleus generated?},
  author={I J Yeh and Eric W. Tsang and Clement Hamani and Elena Moro and Filomena Mazzella and Yu‐Yan W. Poon and Andres M. Lozano and Robert Chen},
  journal={Movement Disorders},
4 Citations
Laterodorsal tegmentum and pedunculopontine tegmental nucleus circuits regulate renal functions: Neuroanatomical evidence in mice models
  • D. Ye, Qing-Qing Guo, Rongchun Li
  • Biology
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
  • 2012
The use of retrograde tracers and fluorescence immunohistochemistry provided direct neuroanatomical foundation for the identification of serotonergic and catecholaminergic projections from the mid-brain tegmentum to the kidney.
Targeting the Pedunculopontine Nucleus: A New Neurophysiological Method Based on Somatosensory Evoked Potentials to Calculate the Distance of the Deep Brain Stimulation Lead From the Obex
Somatosensory evoked potentials may be a helpful tool for calculating the macroelectrode position within the pons during PPTg targeting and was very similar to that issued from the individual brain magnetic resonance imaging.
Uncertainty, misunderstanding and the pedunculopontine nucleus: the exhumation of an already buried dispute
PPTg DBS still requires particular prudence because of the inconsistency of results obtained by different groups, which may limit the correct interpretation of the value of the PPTg as an innovative target, and a constructive and peaceful discussion of all reported cases should accompany any paper concerning PPTG DBS.


Somatosensory input and thalamic projection of pedunculopontine tegmental neurons
The cholinergic pedunculopontine tegmental area of the anesthetized rat was explored for single units responsive to somatosensory stimulation and suggested that somatoensory information is an important element in a subcortical system linking this area with the basal ganglia, superior colliculus and thalamus.
Somatosensory evoked potentials recorded from the human pedunculopontine nucleus region
The results suggest that there are direct somatosensory inputs to the PPNR, and the slow components and HFOs of the SEP have different origins.