Reply: Clinical trials on onabotulinumtoxinA for the treatment of chronic migraine


Dr. Russell raises important points regarding the diagnostic criteria for chronic migraine (CM) and medication overuse headache (MOH). We agree that the definitions for these entities have posed challenges for the past two decades. The ICHD-2 diagnostic criteria for CM and MOH were evolving as the PREEMPT clinical trial program was developed and launched… (More)
DOI: 10.1007/s10194-011-0334-4