Replisome Dynamics during Chromosome Duplication.

@article{Kurth2009ReplisomeDD,
  title={Replisome Dynamics during Chromosome Duplication.},
  author={Isabel Kurth and Mike E O'Donnell},
  journal={EcoSal Plus},
  year={2009},
  volume={3 2}
}
This review describes the components of the Escherichia coli replisome and the dynamic process in which they function and interact under normal conditions. It also briefly describes the behavior of the replisome during situations in which normal replication fork movement is disturbed, such as when the replication fork collides with sites of DNA damage. E. coli DNA Pol III was isolated first from a polA mutant E. coli strain that lacked the relatively abundant DNA Pol I activity. Further… CONTINUE READING
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