Replicator dominance in a eukaryotic chromosome.

  title={Replicator dominance in a eukaryotic chromosome.},
  author={Y Marahrens and Bruce W. Stillman},
  journal={The EMBO journal},
  volume={13 14},
Replicators are genetic elements that control initiation at an origin of DNA replication (ori). They were first identified in the yeast Saccharomyces cerevisiae as autonomously replicating sequences (ARSs) that confer on a plasmid the ability to replicate in the S phase of the cell cycle. The DNA sequences required for ARS function on a plasmid have been defined, but because many sequences that participate in ARS activity are not components of chromosomal replicators, a mutational analysis of… CONTINUE READING

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