Replication of varicella-zoster virus is influenced by the levels of JNK/SAPK and p38/MAPK activation.

@article{Rahaus2004ReplicationOV,
  title={Replication of varicella-zoster virus is influenced by the levels of JNK/SAPK and p38/MAPK activation.},
  author={Markus Rahaus and Nathalie Desloges and Manfred P. H. Wolff},
  journal={The Journal of general virology},
  year={2004},
  volume={85 Pt 12},
  pages={3529-40}
}
Stimulation of the Jun NH(2)-terminal kinase/stress-activated protein kinase (JNK/SAPK) and the p38 mitogen-activated protein kinase (p38/MAPK) is part of the stress-related signal transduction pathways conveying signals from the cell surface into the nucleus in order to initiate programmes of gene expression. Here, it was shown that infection by varicella-zoster virus (VZV) caused a 34-fold increase in activation of JNK/SAPK in the early phase of infection and a 2-fold increase in activation… CONTINUE READING
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