Replication of transmissible gastroenteritis coronavirus (TGEV) in swine alveolar macrophages.

@article{Laude1984ReplicationOT,
  title={Replication of transmissible gastroenteritis coronavirus (TGEV) in swine alveolar macrophages.},
  author={Hubert Laude and Bernard Charley and Jacqueline Gelfi},
  journal={The Journal of general virology},
  year={1984},
  volume={65 ( Pt 2)},
  pages={327-32}
}
Several strains of the enteropathogenic coronavirus transmissible gastroenteritis virus (TGEV) have been shown to replicate in alveolar macrophages maintained in vitro. A distinct cytopathic effect was observed at a multiplicity of infection greater than or equal to 0.1. Infected cells released infectious virus. The extent of both virus production and cell destruction was highly dependent upon the virus input. At low input, cell viability was affected only slightly, and a delayed and persistent… CONTINUE READING

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