Replication of poliovirus in phytohemagglutinin-stimulated human lymphocytes.

Abstract

Poliovirus replication has been studied in human lymphocytes during the course of blastogenesis under phytohemagglutinin (PHA) stimulation. Enhancement of virus replication in PHA-stimulated leukocyte cultures was due to an increase in number of virus-producing cells. Virus yield was approximately 10 plaque-forming units (PFU) per producing cell, both in… (More)

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@article{Willems1969ReplicationOP, title={Replication of poliovirus in phytohemagglutinin-stimulated human lymphocytes.}, author={F. Th. C. Willems and Joseph L. Melnick and William E. Rawls}, journal={Journal of virology}, year={1969}, volume={3 5}, pages={451-7} }