Replication of genetic effects of MC4R polymorphisms on body mass index in a Korean population

@article{Sull2013ReplicationOG,
  title={Replication of genetic effects of MC4R polymorphisms on body mass index in a Korean population},
  author={Jae Woong Sull and Myoungsook Lee and Sun Ha Jee},
  journal={Endocrine},
  year={2013},
  volume={44},
  pages={675-679}
}
Obesity is associated with a variety of adverse health risks. Several genome-wide association studies of obesity have identified candidate genes, including the fat mass and obesity-associated gene (FTO) and the melanocortin-4 receptor (MC4R) gene. We carried out a replication study of MC4R and FTO variants in a Korean cohort. A total of 2,281 subjects in the Bundang-gu region were analyzed using selected markers. Another 8,826 subjects in the Ansung/Ansan city were used for a meta-analysis. Two… CONTINUE READING

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