Replication of epizootic haemorrhagic disease and bluetongue viruses in DH82 cells.

Abstract

Bluetongue viruses (BTV) and epizootic haemorrhagic disease viruses (EHDV) can be propagated in a variety of mammalian cell lines, but in the ruminant host these viruses infect and replicate in endothelium and monocytes/macrophages. In vitro studies of virus-monocyte interactions typically rely on primary ruminant macrophage cultures that cannot be… (More)

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