Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy

@inproceedings{Hamer2014ReplicationOB,
  title={Replication of Brucella abortus and Brucella melitensis in fibroblasts does not require Atg5-dependent macroautophagy},
  author={Isabelle Hamer and Emeline Goffin and Xavier De Bolle and J J Letesson and Michel Jadot},
  booktitle={BMC Microbiology},
  year={2014}
}
Several intracellular bacterial pathogens have evolved subtle strategies to subvert vesicular trafficking pathways of their host cells to avoid killing and to replicate inside the cells. Brucellae are Gram-negative facultative intracellular bacteria that are responsible for brucellosis, a worldwide extended chronic zoonosis. Following invasion, Brucella abortus is found in a vacuole that interacts first with various endosomal compartments and then with endoplasmic reticulum sub-compartments… CONTINUE READING
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