Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations

@article{Rees2011ReplicationO1,
  title={Replication of 13 genome-wide association (GWA)-validated risk variants for type 2 diabetes in Pakistani populations},
  author={Simon Dr Rees and Muhammad Zafar Iqbal Hydrie and Abdus Samad Shera and Sudhesh Kumar and Joseph Paul O’Hare and Anthony Barnett and Abdul Basit and Marilyn Ann Kelly},
  journal={Diabetologia},
  year={2011},
  volume={54},
  pages={1368-1374}
}
Recent genome-wide association (GWA) studies and subsequent replication studies have greatly increased the number of validated type 2 diabetes susceptibility variants, but most of these have been conducted in European populations. Despite the high prevalence of the disease in South Asians, studies investigating GWA-validated type 2 diabetes risk variants in this ethnic group are limited. We investigated 30 single nucleotide polymorphisms (SNPs), predominantly derived from recent GWA studies, to… CONTINUE READING
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