Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels

@inproceedings{Adney2014ReplicationAS,
  title={Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels},
  author={Danielle R. Adney and Neeltje van Doremalen and Vienna R. Brown and Trenton Bushmaker and Dana Scott and Emmie de Wit and Richard A. Bowen and Vincent Munster},
  booktitle={Emerging infectious diseases},
  year={2014}
}
In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isolate of MERS-CoV and a transient, primarily upper respiratory tract infection developed in each of the 3… CONTINUE READING
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