Replication Study Confirms Link between TSPAN18 Mutation and Schizophrenia in Han Chinese

@inproceedings{Yuan2013ReplicationSC,
  title={Replication Study Confirms Link between TSPAN18 Mutation and Schizophrenia in Han Chinese},
  author={Jianmin Yuan and Chunhui Jin and Hai-de Qin and Junjie Wang and Weiwei Sha and Mingzhong Wang and Yunbiao Zhang and Fuquan Zhang and Jijiang Li and Jianfeng Li and Shui Yu and Shuguang Qi and Yin Yao Shugart},
  booktitle={PloS one},
  year={2013}
}
Schizophrenia (SCZ) is a severe psychiatric disorder associated with many different risk factors, both genetic and environmental. A recent genome-wide association study (GWAS) of Han Chinese identified three single-nucleotide polymorphisms (SNPs rs11038167, rs11038172, and rs835784) in the tetraspanins gene TSPAN18 as possible susceptibility loci for schizophrenia. Hoping to validate these findings, we conducted a case-control study of Han Chinese with 1093 schizophrenia cases and 1022 healthy… CONTINUE READING
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