Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression

@inproceedings{Chang2017ReplicationFP,
  title={Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression},
  author={Emily Yun-Chia Chang and Peter C Stirling},
  booktitle={Genes},
  year={2017}
}
Replication-transcription conflicts have been a well-studied source of genome instability for many years and have frequently been linked to defects in RNA processing. However, recent characterization of replication fork-associated proteins has revealed that defects in fork protection can directly or indirectly stabilize R-loop structures in the genome and… CONTINUE READING