Replicating damaged DNA in eukaryotes.

Abstract

DNA damage is one of many possible perturbations that challenge the mechanisms that preserve genetic stability during the copying of the eukaryotic genome in S phase. This short review provides, in the first part, a general introduction to the topic and an overview of checkpoint responses. In the second part, the mechanisms of error-free tolerance in… (More)
DOI: 10.1101/cshperspect.a019836

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