Replicating animal mitochondrial DNA

@inproceedings{McKinney2013ReplicatingAM,
  title={Replicating animal mitochondrial DNA},
  author={Emily A. McKinney and Marcos T Oliveira},
  booktitle={Genetics and molecular biology},
  year={2013}
}
The field of mitochondrial DNA (mtDNA) replication has been experiencing incredible progress in recent years, and yet little is certain about the mechanism(s) used by animal cells to replicate this plasmid-like genome. The long-standing strand-displacement model of mammalian mtDNA replication (for which single-stranded DNA intermediates are a hallmark) has been intensively challenged by a new set of data, which suggests that replication proceeds via coupled leading- and lagging-strand synthesis… CONTINUE READING
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