Replicating DNA does not block germinal vesicle breakdown in mouse oocytes.

@article{Fulka1995ReplicatingDD,
  title={Replicating DNA does not block germinal vesicle breakdown in mouse oocytes.},
  author={Josef Fulka and Robert M Moor},
  journal={The Journal of experimental zoology},
  year={1995},
  volume={272 3},
  pages={245-8}
}
Mouse germinal vesicle GV-G2 stage oocytes were fused to very early S-phase blastomeres from four cell stage embryos to test whether oocytes have a mechanism which detects replicating DNA and thereafter arrests meiosis at the GV stage. Our results show that oocytes are unable to recognize replicating DNA in transplanted nuclei and undergo germinal vesicle… CONTINUE READING