Replenishment of selenium deficient rats with selenium results in redistribution of the selenocysteine tRNA population in a tissue specific manner.

@article{Chittum1997ReplenishmentOS,
  title={Replenishment of selenium deficient rats with selenium results in redistribution of the selenocysteine tRNA population in a tissue specific manner.},
  author={Harold S. Chittum and Kristina E. Hill and Bradley A. Carlson and Byeong Jae Lee and Raymond F. Burk and Dolph Lee Hatfield},
  journal={Biochimica et biophysica acta},
  year={1997},
  volume={1359 1},
  pages={25-34}
}
We reported previously that the selenium status of rats influences both the steady-state levels and distributions of two selenocysteine tRNA isoacceptors and that these isoacceptors differ by a single methyl group attached to the ribosyl moiety at position 34. In this study, we demonstrate that repletion of selenium-deficient rats results in a gradual… CONTINUE READING