Replacement therapy with C1 esterase inhibitors for hereditary angioedema.

  title={Replacement therapy with C1 esterase inhibitors for hereditary angioedema.},
  author={Marco Cicardi and Andrea Zanichelli},
  journal={Drugs of today},
  volume={46 11},
Angioedema due to hereditary C1 inhibitor deficiency (HAE) is a highly disabling and potentially lethal disease with an estimated prevalence of 1:50,000 in the general population worldwide. Treatment of this condition by replacing the deficient protein started shortly after discovery of the underlying genetic defect. Along with other therapeutic approaches developed over the years, C1 inhibitor replacement therapy maintains a central role for the treatment of angioedema attacks in patients with… CONTINUE READING


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