Replacement of specific coagulation factors in patients with burn: a review.

@article{Lavrentieva2013ReplacementOS,
  title={Replacement of specific coagulation factors in patients with burn: a review.},
  author={Athina Lavrentieva},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2013},
  volume={39 4},
  pages={543-8}
}
Major burn is often associated with inflammation and coagulation system activation, consumption of endogenous coagulation factors, which have been associated with adverse clinical outcome. Coagulation system dysfunction during early postburn period is characterized by activation of procoagulation pathways, enhanced fibrinolytic activity and impairment of natural anticoagulants activity. Treatment principles focused on the normalization of coagulation and the inhibition of systemic inflammation… CONTINUE READING