Repetitive transcranial magnetic stimulation of dorsolateral prefrontal cortex increases tolerance to human experimental pain.

@article{GraffGuerrero2005RepetitiveTM,
  title={Repetitive transcranial magnetic stimulation of dorsolateral prefrontal cortex increases tolerance to human experimental pain.},
  author={Ariel Graff-Guerrero and Jorge J. Gonz{\'a}lez-Olvera and Ana Fres{\'a}n and Diana G{\'o}mez-Mart{\'i}n and Juan Carlos M{\'e}ndez-N{\'u}{\~n}ez and Francisco Pellicer},
  journal={Brain research. Cognitive brain research},
  year={2005},
  volume={25 1},
  pages={153-60}
}
Dorsolateral prefrontal cortex (DLPFCx) has been implicated in pain perception and in a pain modulation pathway. However, the precise participation of this region is not completely understood. The aim of this study was to evaluate whether 1 Hz rTMS of DLPFCx modifies threshold and tolerance in experimental pain. The effect of 1 Hz rTMS during 15 min at 100% motor threshold was tested in one hundred and eighty right-handed healthy volunteers, using a parallel-group stimulation design. The… CONTINUE READING

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