Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatment-resistant major depression: a double-blind, randomised, sham-controlled trial.

@article{Bretlau2008RepetitiveTM,
  title={Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatment-resistant major depression: a double-blind, randomised, sham-controlled trial.},
  author={L G Bretlau and Marianne S{\ae}trang Lunde and Lone Lindberg and Mogens Und{\'e}n and Steen Dissing and P. B. Bech},
  journal={Pharmacopsychiatry},
  year={2008},
  volume={41 2},
  pages={
          41-7
        }
}
BACKGROUND The role of high-frequency rTMS over the left cortex as an add-on strategy in the treatment of major depression is still uncertain even in patients resistant to pharmacotherapy. We had planned a large sham TMS controlled study in the acute phase with a placebo-controlled relapse-prevention phase with escitalopram. However, because a recent meta-analysis showed only a small effect size of rTMS over sham TMS in the acute treatment phase of depressed patients, we decided to make an… CONTINUE READING
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