Repetitive firing of rat cerebellar parallel fibres after a single stimulation.

@article{Isope2004RepetitiveFO,
  title={Repetitive firing of rat cerebellar parallel fibres after a single stimulation.},
  author={Philippe Isope and Romain Franconville and Boris Barbour and Philippe Ascher},
  journal={The Journal of physiology},
  year={2004},
  volume={554 Pt 3},
  pages={829-39}
}
The excitatory postsynaptic currents (EPSCs) evoked in Purkinje cells (PCs) by stimulating parallel fibres (PFs) usually show a single peak, but EPSCs with multiple peaks (polyphasic EPSCs) can be observed in slices from animals older than 15 days. The EPSCs remain polyphasic when the postsynaptic current is reduced (either by reducing the intensity of the PF stimulation or by adding AMPA receptor antagonists) and when the PC membrane potential is made positive. Thus the late peaks are not due… CONTINUE READING

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