Repetitive blood sampling in unrestrained and unstressed mice using a chronic indwelling right atrial catheterization apparatus.

A re-usable mobile catheterization apparatus was developed that permits multiple blood samples to be obtained from nonrestrained and unanesthetized mice. The collection end of the catheter is located outside the cage allowing the mouse to remain completely undisturbed prior to and during blood collection. The apparatus was used in adult mice surgically… CONTINUE READING