The somata of molluscan neurones respond with long trains of spikes to steady injected outward current. During such repetitive firing the maximum rate of rise of action potentials usually decreases as a result of inactivation of the transport mechanism for inward current. Significant inactivation of this transport system does not often change the peak level… (More)
Fig. 7- Effect of conditioning pulse upon the outward current traces under voltage-clamp condition, (a) Ringer solution with IO mM Ca2+; (b) Ringer solution with 40 mM Caa+. Holding potential in both solution, — 45 mV. Upper traces, membrane current; lower traces, membrane voltage steps.