Repetin (Rptn), a new member of the "fused gene" subgroup within the S100 gene family encoding a murine epidermal differentiation protein.

@article{Krieg1997RepetinA,
  title={Repetin (Rptn), a new member of the "fused gene" subgroup within the S100 gene family encoding a murine epidermal differentiation protein.},
  author={Peter Krieg and Markus Schuppler and Robert Koesters and Antoaneta Mincheva and Peter Lichter and Friedrich Marks},
  journal={Genomics},
  year={1997},
  volume={43 3},
  pages={339-48}
}
We report the cloning and characterization of a murine epidermal differentiation gene, repetin (Rptn), exhibiting striking similarity to the genes of the intermediate filament-associated proteins profilaggrin and trichohyalin. The repetin gene consists of three exons and two introns. The first exon is short and untranslated. The deduced amino acid sequence distributed between exons II and III contains 1130 amino acids with a calculated molecular mass of 130 kDa and pI of 7.7. The amino terminus… CONTINUE READING
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