Repertoire of antibodies against type 1 poliovirus in human sera.


A blocking-ELISA procedure was used to quantify antibodies in sera of humans immunized with poliovirus vaccines. Titers determined by this method demonstrated an excellent correlation with the results of neutralization test. Testing of serum potency with a panel of type 1 poliovirus strains altered antigenically was used to evaluate the composition of… (More)
DOI: 10.1016/j.jviromet.2010.07.037


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