Reperfusion injury to endothelial cells following cold ischemic storage of rat livers.

@article{CaldwellKenkel1989ReperfusionIT,
  title={Reperfusion injury to endothelial cells following cold ischemic storage of rat livers.},
  author={J C Caldwell-Kenkel and Robert T. Currin and Yuji Tanaka and Ronald G. Thurman and John J. Lemasters},
  journal={Hepatology},
  year={1989},
  volume={10 3},
  pages={292-9}
}
Storage of donor livers in Euro-Collins solution for human transplantation surgery is limited to about 8 hr. Here, tissue damage to isolated rat livers stored under the same conditions as human livers was characterized following reperfusion. The purpose of this work was to determine the importance of nutritional status on injury due to cold storage and reperfusion, to establish whether lethal injury occurs during cold storage or only after reperfusion, and to identify the cell types most… CONTINUE READING

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