Reperfusion injury in skeletal muscle: controlled limb reperfusion reduces local and systemic complications after prolonged ischaemia.

@article{Mitrev1994ReperfusionII,
  title={Reperfusion injury in skeletal muscle: controlled limb reperfusion reduces local and systemic complications after prolonged ischaemia.},
  author={Z. M. Mitrev and Friedhelm Beyersdorf and Rupert Hallmann and Yvonne Poloczek and Kai A. Ihnken and Hardy Herold and Uwe Unkelbach and Guido Zimmer and Hans Joachim Freisleben and Prof. Dr. P. Satter},
  journal={Cardiovascular surgery},
  year={1994},
  volume={2 6},
  pages={
          737-48
        }
}
Previous studies in isolated limbs using crystalloid perfusion solutions have shown that control of the initial reperfusion reduces postischaemic complications. However, no experimental study has been undertaken to evaluate the concept of controlled limb reperfusion experimentally in an in vivo blood-perfused model and to assess the local as well as systemic effects of normal blood reperfusion and controlled limb reperfusion. Of 20 pigs undergoing preparation of the infrarenal aorta and iliac… CONTINUE READING
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