Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle.

@article{Perry2010RepeatedTM,
  title={Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle.},
  author={Christopher G R Perry and James J. Lally and Graham P Holloway and George J. F. Heigenhauser and Arend Bonen and Lawrence L Spriet},
  journal={The Journal of physiology},
  year={2010},
  volume={588 Pt 23},
  pages={
          4795-810
        }
}
Exercise training induces mitochondrial biogenesis, but the time course of molecular sequelae that accompany repetitive training stimuli remains to be determined in human skeletal muscle. Therefore, throughout a seven-session, high-intensity interval training period that increased (12%), we examined the time course of responses of (a) mitochondrial biogenesis and fusion and fission proteins, and (b) selected transcriptional and mitochondrial mRNAs and proteins in human muscle. Muscle biopsies… CONTINUE READING
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