Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathway.

Abstract

Phagocytes of the innate immune system, such as monocytes/macrophages, represent a first line of defense against invading microorganisms. Psychological stress is often thought to suppress the functioning of these cells, in part due to the immunosuppressive activity of stress-induced glucocorticoid hormones. However, exposure to the stressor social… (More)

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