Repeated mechanical loading enhances the expression of Indian hedgehog in condylar cartilage.

@article{Ng2006RepeatedML,
  title={Repeated mechanical loading enhances the expression of Indian hedgehog in condylar cartilage.},
  author={Tonny Ng and K. W. Chiu and A. Bakr M. Rabie and Urban H{\"a}gg},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2006},
  volume={11},
  pages={
          943-8
        }
}
Indian hedgehog (Ihh) acts as a mechanotransduction mediator that converts mechanical strain into cellular proliferation and cartilage formation in mandibular condylar cartilage. The aim of this study was to examine the effect of repeated mechanical strain on the level of expression of Ihh and type II collagen mRNA in condylar growth. Two hundred and eighty 35 days old Sprague-Dawley rats were divided into 10 experimental and 10 control groups. Repeated mechanical loading was applied by… CONTINUE READING

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