Repeated intravenous cocaine administration: locomotor activity and dopamine D2/D3 receptors.

@article{Wallace1996RepeatedIC,
  title={Repeated intravenous cocaine administration: locomotor activity and dopamine D2/D3 receptors.},
  author={Daiana R. Wallace and Charles F. Mactutus and Rosemarie M Booze},
  journal={Synapse},
  year={1996},
  volume={23 3},
  pages={152-63}
}
The dopamine D3 receptor has been implicated as a possible mediator in the reinforcement or abuse of psychostimulants such as cocaine. The present studies examined the effects of repeated (14 day) intravenous cocaine administration (saline vehicle, 0.5, 1.0 and 3.0 mg/kg) on locomotor activity and dopamine D2 and D3 receptor density in the rat striatum and nucleus accumbens. Male Sprague-Dawley rats (n = 40) were implanted with an intravenous access port and allowed to recover for 2 days. An… CONTINUE READING
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…