Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice.

@article{Ahmadi2010RepeatedHP,
  title={Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice.},
  author={Shamseddin Ahmadi and Nazanin Malekmohammadi and Mohammad Reza Zarrindast},
  journal={Archives of Iranian medicine},
  year={2010},
  volume={13 3},
  pages={209-16}
}
BACKGROUND Repeated administration of certain drugs could result in an enhancement of the behavioral effects of those drugs. In the present study, the effect of repeated administration of histamine on amnesia induced by post-training administration of the drug was examined. METHODS A single trial step-down inhibitory (passive) avoidance task was used for memory assessment in male NMRI mice. RESULTS The results showed that post-training administration of different doses of histamine (5, 10… CONTINUE READING