Repeated estradiol benzoate treatment protects against the lordosis-inhibitory effects of restraint and prevents effects of the antiprogestin, RU486.

The following experiment was designed to test two specific questions: (1) Does the antiprogestin, RU486, reduce emergence of lordosis behavior and/or proceptivity in rats given repeated treatment with 10μg estradiol benzoate (EB) and/or a single high dose (40μg) of EB? (2) Does RU486 accentuate the effects of a 5min restraint experience on sexual behaviors… CONTINUE READING