Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds.

@article{ProjectoGarcia2013RepeatedET,
  title={Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds.},
  author={J Projecto-Garcia and Chandrasekhar Natarajan and Hideaki Moriyama and Roy E Weber and Angela Fago and Zachary A. Cheviron and Robert Dudley and Jimmy A Mcguire and Christopher C Witt and Jay F Storz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 51},
  pages={20669-74}
}
Animals that sustain high levels of aerobic activity under hypoxic conditions (e.g., birds that fly at high altitude) face the physiological challenge of jointly optimizing blood-O2 affinity for O2 loading in the pulmonary circulation and O2 unloading in the systemic circulation. At high altitude, this challenge is especially acute for small endotherms like hummingbirds that have exceedingly high mass-specific metabolic rates. Here we report an experimental analysis of hemoglobin (Hb) function… CONTINUE READING

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