Repeated dosing of 23.4% hypertonic saline for refractory intracranial hypertension. A case report.

@article{Valentino2008RepeatedDO,
  title={Repeated dosing of 23.4% hypertonic saline for refractory intracranial hypertension. A case report.},
  author={Alden K. Valentino and Karen M Nau and D. A. Miller and Ricardo A. Hanel and W David Freeman},
  journal={Journal of vascular and interventional neurology},
  year={2008},
  volume={1 4},
  pages={113-7}
}
BACKGROUND Hypertonic saline (HTS) at a concentration of 23.4% is an emerging therapy for intracranial hypertension. Compared to mannitol which can be given as a single bolus or as repeated bolus dosing, little data exists regarding safety or efficacy of repeated dosing of 23.4% HTS. We report the first case of 16 doses of 23.4% HTS over a 5 day period in a… CONTINUE READING