Repeated dose toxicity study of Vibrio cholerae-loaded gastro-resistant microparticles.

Abstract

CONTEXT Microencapsulation of antigens has been extensively studied over the last decades aiming at improving the immunogenicity of vaccine candidates. OBJECTIVE Addressing microparticles (MPs) toxicity in rats. MATERIAL AND METHODS Spray-dried Eudragit® L 30 D-55 MPs and Eudragit® L 30 D-55 alginate MPs were elaborated and characterized. MPs obtained… (More)
DOI: 10.3109/02652048.2013.808278

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