Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine

@article{Dunn2004RepeatedAO,
  title={Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine},
  author={Justin M. Dunn and Brian R. Inderwies and Stephanie C. Licata and R. Christopher Pierce},
  journal={Psychopharmacology},
  year={2004},
  volume={179},
  pages={172-180}
}
Glutamate receptors and their related second messengers in the ventral tegmental area (VTA) are known to play critical roles in the initiation of behavioral sensitization to cocaine. To evaluate the hypothesis that repeated intra-VTA microinjections of the ionotropic glutamate agonist, AMPA, or the metabotropic glutamate agonist, t-ACPD, augment the behavioral hyperactivity induced by a subsequent challenge injection of cocaine. In addition, the dependency of the t-ACPD effect on activation of… CONTINUE READING
Highly Cited
This paper has 27 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

The Rat Brain in Stereotaxic Coordinates

Trends in Neurosciences • 1984
View 3 Excerpts
Highly Influenced