Repeated Short-term (2h×14d) Emotional Stress Induces Lasting Depression-like Behavior in Mice

@inproceedings{Kim2012RepeatedS,
  title={Repeated Short-term (2h×14d) Emotional Stress Induces Lasting Depression-like Behavior in Mice},
  author={Kyoung-Shim Kim and Hye-Joo Kwon and In-Sun Baek and Pyung-Lim Han},
  booktitle={Experimental neurobiology},
  year={2012}
}
Chronic behavioral stress is a risk factor for depression. To understand chronic stress effects and the mechanism underlying stress-induced emotional changes, various animals model have been developed. We recently reported that mice treated with restraints for 2 h daily for 14 consecutive days (2h-14d or 2h×14d) show lasting depression-like behavior. Restraint provokes emotional stress in the body, but the nature of stress induced by restraints is presumably more complex than emotional stress… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Short- and long-term eff ects of intermittent social defeat stress on brainderived neurotrophic factor expression in mesocorticolimbic brain regions

  • S Fanous, RP JrHammer, EM Nikulina
  • Neuroscience
  • 2010
1 Excerpt

Antidepressant actions of histone deacetylase inhibitors

  • HE 3rdCovington, I Maze, +13 authors EJ Nestler
  • J Neurosci
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…