Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue.

@article{Suurmond2016RepeatedFT,
  title={Repeated FcεRI triggering reveals modified mast cell function related to chronic allergic responses in tissue.},
  author={Jolien Suurmond and Kim L L Habets and Zuotian Tatum and Joris J. M. Schonkeren and Peter A. C. 't Hoen and Tom W. J. Huizinga and Jeroen F. J. Laros and Ren{\'e} E. M. Toes and Fina A. S. Kurreeman},
  journal={The Journal of allergy and clinical immunology},
  year={2016},
  volume={138 3},
  pages={869-880}
}
BACKGROUND Activation of mast cells through FcεRI plays an important role in acute allergic reactions. However, little is known about the function of mast cells in patients with chronic allergic inflammation or the effect of repeated FcεRI triggering occurring in such responses. OBJECTIVE We aimed to identify changes in mast cell function after repeated… CONTINUE READING