Repeatability of allergen-induced airway inflammation.

  title={Repeatability of allergen-induced airway inflammation.},
  author={Gail M Gauvreau and Richard M Watson and Tracey Rerecich and E Baswick and Mark D. Inman and Paul M O'Byrne},
  journal={The Journal of allergy and clinical immunology},
  volume={104 1},
BACKGROUND Allergen inhalation challenge is a useful clinical model to investigate the effects of asthma therapies on allergen-induced airway responses; however, the repeatability of allergen-induced airway inflammation is not known. OBJECTIVE The purpose of this study was to investigate the repeatability of allergen-induced increases in sputum eosinophils. This information will allow the prediction of the number of subjects required in studies evaluating asthma therapies. METHODS Seventeen… CONTINUE READING