Repeatability characteristics of simple indices of insulin resistance: implications for research applications.

@article{Mather2001RepeatabilityCO,
  title={Repeatability characteristics of simple indices of insulin resistance: implications for research applications.},
  author={Kieren J Mather and Alice E. Hunt and Helmut O. Steinberg and Giancarlo Paradisi and Ginger Hook and Amos Katz and Michael J. Quon and Alain D. Baron},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 11},
  pages={
          5457-64
        }
}
The objectives of this study were to evaluate test characteristics, such as normality of distribution, variation, and repeatability, of simple fasting measures of insulin sensitivity and to use the results to choose among these measures. Duplicate fasting samples of insulin and glucose were collected before 4 h of euglycemic hyperinsulinemic clamping using insulin infusion rates ranging from 40-600 mU/m2 x min. Currently recommended estimates of insulin sensitivity, including the fasting… CONTINUE READING
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