Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.

@article{Bowen2000RepeatSA,
  title={Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.},
  author={T. Bowen and C. Guy and A. Cardno and J. Vincent and J. L. Kennedy and L. Jones and M. Gray and R. Sanders and G. McCarthy and K. Murphy and M. Owen and M. O’Donovan},
  journal={Psychiatric genetics},
  year={2000},
  volume={10 1},
  pages={
          33-7
        }
}
  • T. Bowen, C. Guy, +9 authors M. O’Donovan
  • Published 2000
  • Biology, Medicine
  • Psychiatric genetics
  • A number of studies using the repeat expansion detection (RED) technique have suggested an association between unknown large CAG/CTG repeats and schizophrenia. The polymorphic CAG/CTG repeat loci CTG18.1 and ERDA1 have been reported to account for a high proportion (approximately 90%) of the large repeats detected by RED and may therefore be responsible for the cited association. The recently described locus TGC13-7a contains a highly polymorphic CTA/TAG and CAG/CTG composite repeat, and is… CONTINUE READING
    9 Citations

    Topics from this paper

    Early development and unstable genes in schizophrenia: preliminary results.
    • 3
    Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia
    • T. Tsutsumi, S. Holmes, +6 authors R. Margolis
    • Medicine
    • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
    • 2004
    • 11
    • Highly Influenced
    The unstable trinucleotide repeat story of major psychosis.
    • 58
    Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results.
    • 92
    • PDF
    Paternal factors and schizophrenia risk: de novo mutations and imprinting.
    • 150
    • PDF
    Mode of transmission of schizophrenia.
    • 4
    An integrative approach for codon repeats evolutionary analyses
    An Application for Studying Tandem Repeats in Orthologous Genes