Repeat induced point mutation in two asexual fungi, Aspergillus niger and Penicillium chrysogenum

@article{Braumann2008RepeatIP,
  title={Repeat induced point mutation in two asexual fungi, Aspergillus niger and Penicillium chrysogenum},
  author={Ilka Braumann and Marco Alexander van den Berg and Frank Kempken},
  journal={Current Genetics},
  year={2008},
  volume={53},
  pages={287-297}
}
Repeat induced point mutation (RIP) is a gene silencing mechanism present in fungal genomes. During RIP, duplicated sequences are efficiently and irreversibly mutated by transitions from C:G to T:A. For the first time, we have identified traces of RIP in transposable elements of Aspergillus niger and Penicillium chrysogenum, two biotechnologically relevant fungi. We found that RIP in P. chrysogenum has affected a large set of sequences, which also contain other mutations. On the other hand, RIP… CONTINUE READING