Repairing the parkinsonian brain with neurotrophic factors

@article{Aron2011RepairingTP,
  title={Repairing the parkinsonian brain with neurotrophic factors},
  author={Liviu Aron and Ruediger Klein},
  journal={Trends in Neurosciences},
  year={2011},
  volume={34},
  pages={88-100}
}
No therapy exists to slow down or prevent Parkinson's disease (PD), a debilitating neurodegenerative disorder. Neurotrophic factors (NTFs) emerged as promising disease-modifying agents in PD and are currently under clinical development. We argue that efforts in three research areas must converge to harness the full therapeutic power of NTFs. First, the physiological roles of NTFs in aging dopaminergic neurons must be comprehensively understood. Second, the mechanisms underlying the… CONTINUE READING

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