Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae.

@article{Bishop1986RepairOH,
  title={Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae.},
  author={Douglas K. Bishop and Richard D Kolodner},
  journal={Molecular and cellular biology},
  year={1986},
  volume={6 10},
  pages={3401-9}
}
Purified heteroduplex plasmid DNAs containing 8- or 12-base-pair insertion mismatches or AC or CT substitution mismatches were used to transform Saccharomyces cerevisiae. Two insertion mismatches, separated by 943 base pairs, were repaired independently of each other at least 55% of the time. This suggested that repair tracts were frequently shorter than 1 kilobase. The two insertion mismatches were repaired with different efficiencies. Comparison of the repair efficiency of one mismatched site… CONTINUE READING