Repair of a proximal femoral bone defect in dogs using a porous surfaced prosthesis in combination with recombinant BMP-2 and a synthetic polymer carrier.

@article{Murakami2003RepairOA,
  title={Repair of a proximal femoral bone defect in dogs using a porous surfaced prosthesis in combination with recombinant BMP-2 and a synthetic polymer carrier.},
  author={Narumichi Murakami and Naoto Saito and Jun Takahashi and Hiroshi Ota and Hiroshi Horiuchi and Masashi Nawata and Takao Okada and Kazutoshi Nozaki and Kunio Takaoka},
  journal={Biomaterials},
  year={2003},
  volume={24 13},
  pages={2153-9}
}
Total hip arthroplasty (THA) has become an almost standard procedure for the treatment of various hip lesions. However, one of the limitations has been the mechanical loosening of the prosthesis, a condition termed peri-prosthetic osteolysis. Consequently, at revision surgery, various grades of bone defect are often noted. Alternative approaches aimed at overcoming this problem have included a special design of the revision prosthesis and allo- or autogeneic bone grafting in combination with or… CONTINUE READING

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